Chronic Consumptive Coagulopathy Secondary to Metastatic Poorly Differentiated Carcinoma: A Case Report and Discussion of Diagnostic Challenges

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Authors

• Casey P. Schukow, Corewell Health East Resident
• Kaylyn Lilly
• Ping L. Zhang, Corewell Health East/Oakland University William Beaumont School of Medicine
• Marc D. Smith, Corewell Health East/Oakland University William Beaumont School of Medicine
• James Z. Huang, Corewell Health East/Oakland University William Beaumont School of Medicine

Description

Introduction • Chronic consumptive coagulopathy is a persistent imbalance between clotting and bleeding, often triggered by underlying conditions like malignancy. • It involves excessive activation of coagulation pathways and depletion of platelets and clotting factors. • One important differential is paraneoplastic hyperfibrinolysis, which is a rare condition where tumor cells excessively activate fibrinolytic systems. • Due to limited literature, this case aims to highlight diagnostic complexities and differentials.

Publication Date

4-15-2026

Keywords

Coagulopathy

Disciplines

Pathology

Recommended Citation

Schukow CP, Lilly K, Zhang PL, Smith MD, Huang JZ. Chronic consumptive coagulopathy secondary to metastatic poorly differentiated carcinoma: a Case report and discussion of diagnostic challenges. Poster presented at 2nd Annual Corewell Health East Medical Education Research Day 2026; 2026 April 15, Virtual.

Comments

2026 2nd Annual Corewell Health East Medical Education Research Day, April 15, 2026