Increased Eosinophils in the Muscularis Propria Without Increased Neutrophils Histologically Supports Symptomatic Acute Appendicitis: A SingleCentered, Retrospective, Quality-Control Study of 21 Cases

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Authors

• Casey P. Schukow, Corewell Health East Resident
• Madison Konja, Oakland University William Beaumont School of Medicine Medical Student
• Zhenhong Qu, Corewell Health East/ Oakland University William Beaumont School of Medicine
• Ping L. Zhang, Corewell Health East/ Oakland University William Beaumont School of Medicine

Description

Background ▪ The presence of neutrophils in muscularis propria is well known to correlate clinically with symptoms of acute appendicitis. ▪ Eosinophils present in the muscularis propria were noted in cases of acute appendicitis in 2000 (Carr, 2000), but the significance of their presence has been unclear, with limited supportive literature. ▪ The goal of this study was to investigate whether increased eosinophils in muscularis propria, without increased neutrophils, could be correlated with clinically diagnosed (symptomatic) acute appendicitis.

Publication Date

4-15-2026

Keywords

Eosinophils, Appendicitis

Disciplines

Pathology

Recommended Citation

Schukow CP, Konja M, Qu Z, Zhang PL. Increased eosinophils in the muscularis propria without increased neutrophils histologically supports symptomatic acute appendicitis: a Single-centered retrospective, quality-control study of 21 cases. Poster presented at 2nd Annual Corewell Health East Medical Education Research Day 2026; 2026 April 15, Virtual.

Comments

Presented at 2nd Annual Corewell Health East Medical Education Research Day 2026; 2026 April 15, Virtual.