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Description

• Clinical trials are essential for advancing treatments in ophthalmology, yet comprehensive data on institutional participation in Phase 3 retina trials is not readily available.

• The U.S. National Library of Medicine Clinical Trials database (NLM database) lists individual research sites for each study; however, aggregating and visualizing this data remains challenging.

• The lack of centralized and easily interpretable data on research site participation hinders understanding of institutional contributions to retinal clinical research.

• Identifying geographic and institutional trends can improve resource allocation and research collaboration.

• We aim to

• Quantify the number of unique institutions participating in Phase 3 clinical retina trials.

• Assess the distribution of trials across research sites.

• Analyze state-level variations in participation.

• Hypothesis

• Institutional participation in Phase 3 retina trials is unevenly distributed, with a concentration in certain geographic regions and academic centers.

• Understanding trial site distribution can inform funding decisions, improve patient access to clinical trials, and guide future research efforts.

• Findings may help stakeholders optimize trial site selection and enhance equity in ophthalmic research participation.

Publication Date

5-2025

Keywords

Clinical trials, ophthalmology

Disciplines

Ophthalmology

Comments

The Embark Capstone Colloquium at the Oakland University William Beaumont School of Medicine, Rochester Hills, MI, May, 2025.

A Quantitative Analysis on the Locations of Phase 3 Retina Trials in the United States over the past 5 Years

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Ophthalmology Commons

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