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Description
Familial exudative vitreoretinopathy, or FEVR, defines a group of inherited retinal diseases marked by abnormal blood vessel growth in the retina, causing poor vascular development in the peripheral retina. It is linked to increased vessel permeability and may result in retinal ischemia, exudative retinal detachment, and subsequent vision loss. It can be inherited through autosomal dominant, autosomal recessive, or X-linked recessive patterns. There is no definitive treatment or cure, but is treated based on staging of disease on an individual case-by-case basis. Genomics is a rapidly growing field in personalized medicine. Targeted next-generation sequencing (NGS) enables fast and cost-effective identification of genetic variations. NGS allows for the simultaneous sequencing of millions of base pairs of genetic information in just hours.
Publication Date
5-2025
Keywords
Familial exudative vitreoretinopathy
Disciplines
Ophthalmology
Recommended Citation
Stepanian R, Abdekmessih G, Drenser K, Capone A Jr, Trese MT. Custom gene panel sequencing of FEVR patients and family members. Poster presented at: Oakland University William Beaumont School of Medicine Embark Capstone Colloquium; 2025 May; Rochester Hills, MI.
Comments
The Embark Capstone Colloquium at the Oakland University William Beaumont School of Medicine, Rochester Hills, MI, May, 2025.