Perioperative Challenges in Myasthenia Gravis: A Case of Liver Transplantation

Authors

Revati Rashingkar, Oakland University William Beaumont School of Medicine Medical Student
Farah Aboufakhr, Corewell Health East Resident
Roy Soto, Corewell Health East

Document Type

Conference Proceeding

Publication Date

10-12-2025

Abstract

A 64-year-old male with myasthenia gravis post-thymectomy, alpha-1 antitrypsin deficiency, and chronic anemia underwent liver transplantation for decompensated cirrhosis secondary to alcohol use. He was maintained on corticosteroids without pyridostigmine preoperatively. Pulmonary function testing revealed moderate restrictive physiology with low maximal voluntary ventilation, consistent with neuromuscular weakness. He underwent 10 hours of general anesthesia and was intubated for 20 hours. In this case, we will discuss anesthetic planning and intraoperative management in patients with myasthenia gravis, as well as notable perioperative complications such as prolonged intubation and respiratory insufficiency that are less common in non-myasthenic patients.

Comments

American Society of Anesthesiologists, The Anesthesiology Annual Meeting, October 10-14, 2025, San Antonio, TX

Recommended Citation

Rashingkar R, Aboufakhr F, Soto R. Perioperative challenges in myasthenia gravis: a case of liver transplantation. Presented at: American Society of Anesthesiologists, The Anesthesiology Annual Meeting; 2025 Oct 12; San Antonio, TX. Available from:https://www.abstractsonline.com/pp8/#!/21028/presentation/10091