Sarcopenia and sarcopenic obesity in type 2 diabetes mellitus and cardiovascular disease: current perspective and narrative review.

Document Type

Article

Publication Date

11-2025

Publication Title

Endocrine Regulations

Abstract

Sarcopenia, initially described as a disease of the elderly and its coexistence with obesity, now termed as 'sarcopenic obesity' (SO), are now emerging to be important health problems worldwide. Their relatively recent recognition as distinct clinical entities with growing research has shown an increasing prevalence of both sarcopenia and SO. There is a strong independent association, which exists between sarcopenia/SO, type 2 diabetes mellitus (T2DM), and cardiovascular disease (CVD). Studies investigating prevalence of sarcopenia/SO indicate considerable heterogeneity, likely due to the lack of a universally accepted definition, differences in age groups, gender, ethnicity, and socio-demographic factors of the population studied, apart from use of distinct diagnostic criteria and methods of estimation based on either muscle mass or strength.

Volume

59

Issue

1

First Page

199

Last Page

205

DOI

10.2478/enr-2025-0023

ISSN

1336-0329

PubMed ID

41217055

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