Autoimmune Fulminant Myopericarditis Presenting as Cardiac Tamponade-A Rare Occurrence in a Patient with Systemic Lupus Erythematosus.

Document Type

Article

Publication Date

2025

Publication Title

JRSM Cardiovascular Disease

Abstract

Cardiac tamponade is a rare, life-threatening condition caused by accumulation of pericardial fluid, leading to rapid changes in hemodynamic status. Common causes include cancer, chest trauma, pericarditis, autoimmune diseases, and infectious agents such as viruses, bacteria, and fungi. Patients typically present with symptoms of weakness, chest pain, and shortness of breath. We present the case of a young female who presented with obstructive shock and echocardiographic evidence of tamponade. She was worked up and found to have cardiogenic shock likely secondary to systemic lupus erythematosus and fulminant myopericarditis. Prompt intervention with pericardiocentesis of 250 mL of exudative fluid led to significant improvement in left ventricle function and hemodynamic stability. The case highlights the importance for early recognition and a broad differential diagnosis-including autoimmune causes-when evaluating potential tamponade.

Volume

14

First Page

20480040251368556

Last Page

20480040251368556

DOI

10.1177/20480040251368556

ISSN

2048-0040

PubMed ID

40808968

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