A Young Patient with Chronic Pain and Suspected Ehlers-Danlos Syndrome and Postural Orthostatic Tachycardia Syndrome

Document Type

Conference Proceeding

Publication Date

10-18-2026

Abstract

A 19-year-old male with history of Burkitt’s leukemia in remission, chronic joint pain, and hypermobility syndrome presented with fatigue and symptoms of orthostatic intolerance concerning for postural orthostatic tachycardia syndrome as well as Ehlers-Danlos syndrome. He has had persistent fatigue, syncope, and functional limitation despite multidisciplinary management, including pain medicine involvement. Cardiac evaluation included ambulatory monitoring with planned tilt-table testing. Symptom improvement was partially achieved with a multimodal pain regimen including low-dose naltrexone. This case highlights the complexity of chronic pain management in patients with suspected connective tissue and autonomic disorders and emphasizes a multidisciplinary, individualized approach to care.

Comments

American Society of Anesthesiologists, The Anesthesiology Meeting, October 16-20, 2026, San Diego, CA

Share

COinS