Temperature Matters: Rocuronium Storage Conditions and Incomplete Neuromuscular Blockade in a Complex Pancreaticoduodenectomy

Authors

Hashim Aslam, Oakland University William Beaumont School of Medicine Medical Student
Maya Jaradi, Oakland University William Beaumont School of Medicine Medical Student
Eric Battista, Corewell Health East Resident
Roy G. Soto, Corewell Health East

Document Type

Conference Proceeding

Publication Date

10-12-2025

Abstract

We present the case of a 66 year old male undergoing a Whipple procedure who received rocuronium for muscle relaxation. Suspected incomplete motor blockade led to patient movement requiring increased NMBA dosing and highlighted reduced rocuronium efficacy. Postoperative investigation revealed that the rocuronium had been stored outside the recommended refrigerated conditions. Improper storage may impact the time of onset, duration, and recovery of paralytic medications. We will review the need for further investigation into best practices for NMBA storage and use in prolonged surgeries to ensure optimal drug potency and patient safety.

Comments

American Society of Anesthesiologists, The Anesthesiology Annual Meeting, October 10-14, 2025, San Antonio, TX

Recommended Citation

Aslam H, Jaradi M, Battista E, Soto RG. Temperature matters: rocuronium storage conditions and incomplete neuromuscular blockade in a complex pancreaticoduodenectomy. Presented at: American Society of Anesthesiologists, The Anesthesiology Annual Meeting; 2025 Oct 12; San Antonio, TX. Available from:https://www.abstractsonline.com/pp8/#!/21028/presentation/9268