Concurrent intraductal papilloma and nipple adenoma: a case report and review of the literature.

Document Type

Article

Publication Date

5-24-2026

Publication Title

J Surg Case Rep

Abstract

Nipple adenoma is a rare benign proliferative lesion that makes up < 1% of diagnosed benign breast lesions. The diagnosis of an intraductal papilloma is more common and represents an estimated 2%-3% of all benign breast tumours. The concomitant diagnoses of these pathologies together is extremely rare. Here, we report the case of a 34-year-old female that presented with a left-sided nipple lesion discovered on self-exam. Subsequent imaging was classified as BIRADS 4A and the patient opted to undergo surgical excision. Resultant pathology revealed both nipple duct adenoma and intraductal papilloma with florid ductal hyperplasia and focal atypia. Given the rarity of underlying nipple pathologies and the associated diagnostic difficulties, a thorough and complete workup is crucial even when benign breast pathology is suspected.

Volume

2026

Issue

5

First Page

rjag381

Last Page

rjag381

DOI

doi.org/10.1093/jscr/rjag381

ISSN

2042-8812

PubMed ID

42186517

Link to Full Text

Share

COinS