Toxicity and Clinical Outcomes Following Brachytherapy Using 3-D Dosimetric Planning in Patients with Cervical Cancer: An Institutional Experience

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Authors

Nikita M. Patel, Oakland University William Beaumont School of Medicine Medical Student
Jacob F. Oyeniyi, Corewell Health East Resident
Maha Saada Jawad, Corewell Health East

Description

• Cervical cancer is the most common gynecological cancer worldwide.1

• The standard of care for locally advanced cervical cancer (LACC) includes primary chemoradiation, brachytherapy, and external-beam radiotherapy.2

• Brachytherapy (BT) involves the targeted delivery of radiation to the cervix (Fig 1). However, radiation can be toxic to surrounding structures, most commonly affecting the gynecological, genitourinary, and gastrointestinal systems.3

• Historically, brachytherapy was planned using a 2-D approach, which had limitations in accuracy and increased toxicity to the adjacent bowel and bladder. 3-D planning using CT or MRI has been shown to have improved dose precision and reduced toxicity.4

• This study aims to evaluate toxicity and clinical outcomes for patients treated at our institution utilizing this method, contributing to existing literature and assessing institutional results.

Publication Date

5-2025

Keywords

Cervical cancer, locally advanced cervical cancer, Brachytherapy

Disciplines

Oncology | Radiation Medicine

Recommended Citation

Patel NM, Oyeniyi JF, Jawad MS. Toxicity and clinical outcomes following brachytherapy using 3-D dosimetric planning in patients with cervical cancer: an institutional experience. Poster presented at: Oakland University William Beaumont School of Medicine Embark Capstone Colloquium; 2025 May; Rochester Hills, MI.

Comments

The Embark Capstone Colloquium at the Oakland University William Beaumont School of Medicine, Rochester Hills, MI, May, 2025.