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  • In women with breast cancer requiring whole breast irradiation therapy (WBI), current guidelines endorse moderately hypofractionated whole breast irradiation (HWBI), which includes a shorter, 3-4-week regimen of radiation with a higher dose per daily fraction in comparison to conventional whole breast irradiation (CWBI), which includes a 5-6.5-week regimen.
  • Patients with certain risk factors may benefit from treatment to the regional lymph nodes (RNI), which include the ipsilateral axillary, internal mammary and supraclavicular chains.
  • Some centers have been slower to adopt short-course treatment when regional lymph nodes also require treatment (H-RNI), despite a reduction in the number of treatments for the patient, less restriction on time for the treating facility and an increase in cost effectiveness for hospital systems. This is in part due to the lack of data surrounding the use of H-RNI.
  • In this study, we report the acute and chronic toxic effects in patients treated with H-RNI.

Publication Date

5-2024

Keywords

neoplasm, breast

Disciplines

Oncology | Radiology

Comments

The Embark Capstone Colloquium at the Oakland University William Beaumont School of Medicine, Rochester Hills, MI, May, 2024.

Hypofractionated Regional Nodal Irradiation in Breast Cancer

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