Document Type

Conference Proceeding

Publication Date

1-8-2025

Publication Title

American Journal of Health-System Pharmacy

Abstract

Purpose: Colorectal and hysterectomy surgeries can expose patients to various bacterial organisms which can increase their risk of surgical site infections. The most common offending bacteria include Bacteroides fragilis, Escherichia coli, and other obligate anaerobes. Per the institution’s policy, cefazolin plus metronidazole is the preferred prophylactic antibiotic regimen in colorectal and hysterectomy surgeries. However, patient allergies or physician preference may lead towards utilization of alternative antibiotic therapy. This study will evaluate the number of patients who received antibiotics in accordance with the hospital guidelines, prior to colorectal and hysterectomy surgeries. Methods: This study will be a retrospective chart review including adult patients aged 18 and older who underwent colorectal or hysterectomy surgery at Corewell Health Beaumont Troy Hospital from January 1st,2024 to June 30th, 2024. Patients who died intraoperatively and patients presenting with intra-abdominal infection prior to surgical intervention are excluded from the study. Patient information will be obtained through the EPIC electronic medical record. The primary outcome is to assess the number of patients who received treatment adherent to current Corewell Health Beaumont Troy Hospital guidelines for perioperative antibiotic prophylaxis in colorectal and hysterectomy surgeries. The secondary outcomes are to characterize alternative antibiotics used, antibiotic allergies, and surgical site infection within 30- and 90-days post-surgery. Descriptive statistics will be used to evaluate outcomes.

Volume

82

Issue

Suppl 1

First Page

S859

Last Page

S859

Comments

2024 ASHP (American Society of Health-System Pharmacists) Midyear Clinical Meeting, December 8-12, 2024, New Orleans, LA

DOI

10.1093/ajhp/zxae345

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