Cost Avoidance Associated with Aspirin De-Prescribing Among Patients Receiving Warfarin.

Document Type

Article

Publication Date

3-24-2026

Publication Title

TH open : companion journal to thrombosis and haemostasis

Abstract

BACKGROUND: From 2017 to 2018, the Michigan Anticoagulation Quality Improvement Initiative (MAQI

OBJECTIVE: To determine the amount reimbursed from insurance for bleeding and thrombotic events; to estimate the reimbursement savings from our antithrombotic stewardship intervention in US dollars.

METHODS: Insurance claims data were linked to the MAQI

RESULTS: Major bleeding events were associated with a median inpatient/emergency department (ED) cost of $13,661 (IQR: $6,601). Nonmajor bleeding events had a median inpatient cost of $11,678 (IQR: $6,050) and a median ED cost of $457 (IQR: $517). Major bleeding events were reduced by 1.3 bleeds per 100-patient-years postintervention for a savings of $17,759 per 100-patient-years. Nonmajor bleeding was reduced by 8.5 bleeds per 100-patient-years postintervention, for a savings of $26,535 per 100-patient-years. Thrombosis rates were similar pre- and postintervention. Overall estimated savings are $44,294 per 100-patient years or $443 per patient annually.

CONCLUSION: Our antithrombotic stewardship intervention was associated with healthcare system payment savings and improved patient outcomes.

Volume

10

First Page

28333348

DOI

10.1055/a-2833-3348

ISSN

2512-9465

PubMed ID

41970615

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