Factors Associated With Invasive Extraoperative Electroencephalography Monitoring in Pediatric Drug-Resistant Epilepsy Due to Focal Cortical Dysplasia
Document Type
Conference Proceeding
Publication Date
12-6-2025
Abstract
Rationale: Focal cortical dysplasia (FCD) is the most common cause of surgically treatable, drug-resistant epilepsy (DRE) in children. Surgical teams may use one-stage (without extraoperative intracranial monitoring) or two-stage (intracranial monitoring followed by further surgery) approaches; however, the factors associated with this decision is not well understood. This study aims to compare patient characteristics and outcomes of children with FCD-DRE between one-stage and two-stage surgeries. Methods: We performed a retrospective analysis of children < 18-year-old with FCD-DRE from the multicenter, prospective Pediatric Epilepsy Research Consortium (PERC) Surgery Database. Variables analyzed included demographics, seizure characteristics, imaging results, and surgical details between one- and two-stage procedures. Outcomes were compared between the two groups for patients with at least 6 months follow-up. Stepwise logistic regression model was used to identify predictors of two-stage surgery.
Recommended Citation
Karakas C, Perry MS, Caraway A, Novotny E, Depositario-Cabacar D, Gaillard W, et al. [McNamara N]. Factors associated with invasive extroperative electroencephalography monitoring in pediatric drug-resistant epilepsy due to focal cortical dysplasia. Presented at: American Epilepsy Society Annual Meeting; 2025 Dec 6; Atlanta, GA. Available from:https://aesnet.org/abstractslisting/factors-associated-with-invasive-extraoperative-electroencephalography-monitoring-in-pediatric-drug-resistant-epilepsy-due-to-focal-cortical-dysplasia
Comments
American Epilepsy Society Annual Meeting, December 5-9, 2025, Atlanta, GA