Utilizing Lesion Diameter and Prostate Specific Antigen Density to Decide on Magnetic Resonance Imaging Guided Confirmatory Biopsy of Prostate Imaging Reporting and Data System Score Three Lesions in African American Prostate Cancer Patients Managed With Active Surveillance.

Document Type

Article

Publication Date

4-2022

Publication Title

International Urology and Nephrology

Abstract

OBJECTIVE: The objective of the study is to identify the rate of significant prostate cancer (PCa) detection in PI-RADS3 lesions in AA patients stratified by PSAD threshold of <  0.15 vs. ≥ 0.15 ng/ml

METHODS: We analyzed our institutional database of MRI-TB to identify the rate of significant prostate cancer (PCa) detection in PI-RADS3 lesions in AA patients stratified by PSAD threshold of <  0.15 vs. ≥ 0.15 ng/ml

RESULTS: Of 768 patients included in the database, 211 (27.5%) patients identified themselves as AAs. Mean age of AA patients was 63 years and mean PSAD was 0.21. Sixty nine (32.7%) AA patients were found to have PI-RADS 3 lesions. Mean PSAD of AA patients with PI-RADS 3 lesions was 0.21 ng/ml

CONCLUSIONS: We report on the performance of a reported PSAD density threshold in detecting significant PCa in one of the largest series of AA patients receiving MRI-TB of the prostate. Our results have direct clinical implications when counseling AA patients with PI-RADS 3 lesion on whether they should undergo MRI-TB of such lesions.

Volume

54

Issue

4

First Page

799

Last Page

803

DOI

10.1007/s11255-022-03136-1

ISSN

1573-2584

PubMed ID

35138582

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