Rodent Stroke Models to Study Functional Recovery and Neural Repair
Document Type
Article
Publication Date
1-1-2023
Publication Title
Methods in molecular biology (Clifton, N.J.)
Abstract
Rodent ischemic stroke models are essential research tools for studying this highly prevalent disease and represent a critical element in the translational pipeline for development of new therapies. The majority of ischemic stroke models have been developed to study the acute phase of the disease and neuroprotective strategies, but a subset of models is better suited for studying stroke recovery. Each model therefore has characteristics that lend itself to certain types of investigations and outcome measures, and it is important to consider both explicit and implicit details when designing experiments that utilize each model. The following chapter briefly summarizes the known aspects of the main rodent stroke models with emphasis on their clinical relevance and suitability for studying recovery and neural repair following stroke.
Volume
2616
First Page
3
Last Page
12
Recommended Citation
Britsch DRS, Syeara N, Stowe AM, Karamyan VT. Rodent Stroke Models to Study Functional Recovery and Neural Repair. Methods Mol Biol. 2023;2616:3-12. doi:10.1007/978-1-0716-2926-0_1
DOI
10.1007/978-1-0716-2926-0_1
ISSN
1940-6029
PubMed ID
36715922