Titanium Allergy: An Uncommon Cause of Pain in Cochlear Implant Recipients.
Document Type
Article
Publication Date
3-1-2026
Publication Title
Otology & Neurotology
Abstract
OBJECTIVE: To describe the clinical presentation and course of 2 cochlear implant (CI) recipients with a titanium allergy.
PATIENTS: A 66-year-old female and a 41-year-old female both underwent unilateral cochlear implantation, immediately after which they experienced otalgia that persisted and negatively impacted their ability to wear their CI external processor.
INTERVENTIONS: Patch testing for cochlear implant allergy was performed. Surgical explantation of the CI with the exposed titanium to remove the allergen was recommended, with a subsequent surgery offered with implantation of a CI fully encased in silicone after resolution of otalgia.
MAIN OUTCOME MEASURES: Clinical resolution of otalgia, including the ability to use a cochlear implant without discomfort.
RESULTS: Both CI patients were confirmed to have a titanium allergy through patch testing. One patient experienced complete resolution of otalgia, while the second patient continued to have otalgia for at least 6 months following CI explantation. The first patient was subsequently implanted with a different CI in which the titanium components were fully encased in silicone and has remained pain-free and able to use her CI on an everyday basis 2 years post-implantation.
CONCLUSIONS: A high index of suspicion for patient allergy to cochlear implants is warranted in CI recipients presenting with otherwise unexplained and persistent otalgia following CI surgery, and even more so in those with a prior history of hypersensitivity reactions.
Volume
47
Issue
3
First Page
522
Last Page
522
Recommended Citation
Hong AC, Lucas JC. Titanium Allergy: An Uncommon Cause of Pain in Cochlear Implant Recipients. Otol Neurotol. 2026 Mar 1;47(3):e522-e524. doi: 10.1097/MAO.0000000000004783. Epub 2025 Dec 9. PMID: 41361686.
DOI
10.1097/MAO.0000000000004783
ISSN
1537-4505
PubMed ID
41361686