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Description
Periprosthetic joint infection (PJI) is a devastating complication of one of the most successful surgeries in medicine. About 1% to 2% of patients will develop PJI after primary total hip arthroplasty (THA) or primary total knee arthroplasty (TKA) [1]. The 5-year patient survival rate of THA PJI is estimated to be worse than that of common cancers, such as breast cancer [2]. The burden of this disease is likely to increase exponentially as the population ages and the number of patients undergoing total joint arthroplasties increases in the future [3].
Most devastating is what Murray et al deem as metachronous periprosthetic joint infection (MPJI) in which patients are surgically treated for an initial PJI and then develop a subsequent PJI at a second site [4]. The incidence of MPJI has been estimated to be between 6.3% and 20% [5-6]. There has been a discordance in the risk factors for MPJI, as reported in several existing studies. Most evidence has supported rheumatoid arthritis, sepsis or systemic inflammatory response syndrome at the time of initial PJI, MRSA-positive intraoperative cultures, more than 3 stages of resection arthroplasty, longer length of hospitalization, and an index knee prosthesis as the likely risk factors.
Publication Date
5-2025
Disciplines
Orthopedics
Recommended Citation
Young D, Nikolaidis D, Steffensmeier A, Runner R, Karadsheh M. Metachronous periprosthetic joint infection in patients with multiple arthroplasties at index infection. Poster presented at: Oakland University William Beaumont School of Medicine Embark Capstone Colloquium; 2025 May; Rochester Hills, MI.
Comments
The Embark Capstone Colloquium at the Oakland University William Beaumont School of Medicine, Rochester Hills, MI, May, 2025.