Second-Site Periprosthetic Joint Infection After Subsequent Primary Hip or Knee Arthroplasty

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Authors

Daniel Nikolaidis, Oakland University William Beaumont School of Medicine Medical Student
Devin Young, Oakland University William Beaumont School of Medicine Medical Student
Andrew Steffensmeier
Robert Runner, Corewell Health East
Mark Karadsheh, Corewell Health East

Description

Periprosthetic joint infections (PJI) can arise anytime in the lifetime of a patient. Therefore, patients who have multiple prosthetic joints are at risk for developing multiple PJIs. Polyarticular PJI can be classified as either synchronous or metachronous. Synchronous PJIs present simultaneously in two or more joints. Metachronous PJIs (MPJI) occur in two or more joints after a disease-free period. Incidence of MPJI varies in the literature from 8-20%.1

Known risk factors associated with MPJI include Rheumatoid Arthritis, sepsis or SIRS, infection with MRSA, ≥3 revision arthroplasties, longer length of stay in the hospital, and an index TKA PJI.2

Only a few studies specifically investigate MPJI in subsequent primary arthroplasties. These studies suggest that patients who have a history of treated PJI are at an increased risk of developing a MPJI in a second arthroplasty site.3-5

Publication Date

5-2025

Keywords

Periprosthetic joint infections

Disciplines

Orthopedics

Recommended Citation

Nikolaidis D, Young D, Steffensmeier A, Runner R, Karadsheh M. Second-site periprosthetic joint infection after subsequent primary hip or knee arthroplasty. Poster presented at: Oakland University William Beaumont School of Medicine Embark Capstone Colloquium; 2025 May; Rochester Hills, MI.

Comments

The Embark Capstone Colloquium at the Oakland University William Beaumont School of Medicine, Rochester Hills, MI, May, 2025.