Near-infrared photobiomodulation stimulates viability and cartilage matrix synthesis in human chondrocytes.

Document Type

Article

Publication Date

12-29-2025

Publication Title

Scientific reports

Abstract

Photobiomodulation (PBM) within red to near-infrared spectrum has been proposed as a method to restore articular cartilage injuries, due to its ability to modulate effectively chondrocyte activity, namely viability, proliferation and extracellular matrix synthesis. This in vitro study aimed to determine the most appropriate PBM dosage on human chondrocytes. Firstly, human chondrocytes were stimulated daily or every other day with light-emitting diodes (LEDs) at wavelengths of 600-940 nm and power densities of 4-17 mW/cm

Volume

15

Issue

1

First Page

44885

DOI

10.1038/s41598-025-28792-y

ISSN

2045-2322

PubMed ID

41462543

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