Non-invasive biomarkers in assisted reproductive technologies, current evidence, clinical utility and future perspectives.
Document Type
Article
Publication Date
7-2-2026
Publication Title
Frontiers in reproductive health
Abstract
Although assisted reproductive technologies have significantly advanced the treatment of infertility, overall success rates remain limited by the lack of accurate and safe tools for assessing reproductive potential. Conventional embryo selection and endometrial evaluation rely largely on morphological and non-functional criteria, which provide only indirect insight into the underlying biological competence of the embryo oocyte and uterine environment. In this context the development of non-invasive biomarkers has emerged as a critical objective in modern reproductive medicine. This review discusses current evidence on non-invasive biomarkers in
Volume
8
First Page
1875776
Recommended Citation
Zikopoulos A, Sesse A, Katopodis P, Katopodi AT, Paraschos VS, Filiponi M et al Non-invasive biomarkers in assisted reproductive technologies, current evidence, clinical utility and future perspectives. Front Reprod Health. 2026 Jul 2;8:1875776. doi: 10.3389/frph.2026.1875776. PMID: 42465850
DOI
10.3389/frph.2026.1875776
ISSN
2673-3153
PubMed ID
42465850