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Description

Autoimmune diseases often co-exist given the non-specific nature of the immune response. For example, myasthenia gravis [MG], a well-established autoimmune disease, has a 2.36-fold increased risk of developing thyroid diseases as compared to normal controls. 1,2 In contrast, multiple sclerosis [MS] is a disorder in which the immune system subserves an important pathogenic role, although there is insufficient evidence to definitively classify it as an autoimmune disease. 3,4 Since the etiology of MS has yet to be identified, and the specific autoimmune mechanism requires further elucidation, the comparison of its coassociated autoimmune diseases with that of a well-studied neuroautoimmune disease, MG, may provide direction for future studies looking into the pathophysiology and autoimmune mechanism of MS. In order to further explore the coexistence of autoimmune disorders, this study compared the association of concordant autoimmune diseases between MG and MS patients, using migraine, a non-autoimmune neurological disorder, as a control group.

Publication Date

5-2024

Keywords

Autoimmune diseases, myasthenia gravis

Disciplines

Neurology

Comments

The Embark Capstone Colloquium at the Oakland University William Beaumont School of Medicine, Rochester Hills, MI, May, 2024.

Comparison of Associated Autoimmune Disease Diagnoses in Myasthenia Gravis and Multiple Sclerosis Patients

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