More than Seizure Control: Multidimensional Outcome Reporting in Epilepsy (MORE) as a Patient-centered Framework Redefining Success in Treatment.

Document Type

Article

Publication Date

2025

Publication Title

Epilepsia

Abstract

The Multidimensional Outcome Reporting in Epilepsy (MORE) framework addresses critical limitations in current epilepsy outcome assessment by combining seizure control, quality of life, and patients' subjective experience. Although seizure frequency is the main emphasis of traditional classifications, they overlook important aspects of patients' experience such as treatment burden, psychosocial well-being, and functional outcomes. This framework uses a 40-40-20 weighting model in three different domains and includes proven quality of life measures. Implementation issues include consideration of the subjective aspects of assessment, standardizing across settings, and integrating clinical workflow. Eleven subdomains that cover important facets of postoperative epilepsy care are included in MORE. With simple questions, these subdomains can be evaluated effectively at a standard clinic visit. The nature of the framework permits adaption to both adult and pediatric populations while upholding fundamental concepts. MORE is more in line with the principles of patient-centered care and has the potential to influence future consensus-driven outcome definitions in the field, making it an (essential consideration given the advancement of epilepsy care.

Comments

Helen DeVos Children's Hospital

DOI

10.1111/epi.18471

ISSN

1528-1167

PubMed ID

40402032

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