A Case of Rivaroxaban-Induced Acute Tubulointerstitial Nephritis

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Authors

Kali Gray, Corewell Health East Fellow
Kelly Mercier, Corewell Health East

Description

• Direct oral anticoagulants have garnered increasing popularity over the past several years and have largely replaced the use of warfarin in the treatment of certain conditions such as atrial fibrillation and the prevention and treatment of thromboembolism.

• Rivaroxaban is one of the most commonly used direct oral anticoagulants. It is 66% renally-cleared and a common side effect is renal impairment of which the pathophysiology has been unclear.

• There have been case reports of rivaroxaban-induced acute tubulointerstitial nephritis. Here we present an additional case of acute tubulointerstitial nephritis, most likely caused by rivaroxaban.

Publication Date

3-13-2025

Keywords

oral anticoagulants

Disciplines

Nephrology

Recommended Citation

Gray K, Mercier K. A case of rivaroxaban-induced acute tubulointerstitial nephritis. Presented at Corewell Health Hospital Farmington Hills 2025 Alvin Yarrows Research Day; 2025 Mar13; Farmington Hills, MI.

Comments

2025 Alvin Yarrows Research Day at Corewell Health Hospital Farmington Hills, Farmington Hills, MI, March 13, 2025.