Document Type

Conference Proceeding

Publication Date

6-2025

Publication Title

Research and Practice in Thrombosis and Haemostasis

Abstract

Background : Disseminated intravascular coagulation (DIC) is a serious and often life-threatening condition that can result in widespread morbidity and mortality. Despite its clinical significance, there remains a lack of comprehensive, national-level data analyzing trends in DIC-related mortality. Understanding these trends is crucial for identifying at-risk populations, informing public health strategies, and optimizing clinical interventions. Aims : This study aims to analyze DIC mortality trends from 2018 to 2023, focusing on key demographic and regional factors, to provide insights that can guide future healthcare policy and practice. Methods : An analysis of DIC mortality trends from 2018 to 2023 was conducted using the CDC WONDER database. Mortality data were stratified across variables, including age cohorts, gender distributions, state-level geographic regions, degrees of urbanization, and racial/ethnic classifications. Descriptive statistical methodologies were used to synthesize and identify patterns and trends within the mortality data. Results : From 2018 to 2023, Texas had the highest deaths, with 40.4% (36 cases) of the 89 nationwide deaths, followed by California and New York at 23.6% (21 cases each). Most deaths occurred in urban areas, with 75.3% (67 cases) in Large Central Metro areas, and 12.4% (11 cases) each in Large Fringe and Medium Metro areas. The 65-74 age group had the highest mortality at 40.4% (36 cases), followed by 55-64 years at 24.7% (22 cases), 75-84 years at 23.6% (21 cases), and 85+ years at 11.2% (10 cases). Female deaths made up 87.6% (78 cases), while male deaths were 12.4% (11 cases). White individuals accounted for 88.8% (79 cases) of deaths, and Black individuals 11.2% (10 cases). Conclusion(s) : California and Texas emerged as states with notably high mortality figures, particularly among females. Urban areas and older adults were also most affected. These findings suggest a need for targeted health interventions in these regions, with a particular focus on older women.

Volume

9

Issue

Suppl 2

First Page

35

Comments

2025 Congress of the International Society of Thrombosis and Haemostasis, June 21-25, 2025, Washington, DC

Last Page

36

DOI

10.1016/j.rpth.2025.102923

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