Efficacy and safety of endoscopic transcecal appendectomy: a systematic review and meta-analysis.

Document Type

Article

Publication Date

5-15-2026

Publication Title

Translational gastroenterology and hepatology

Abstract

BACKGROUND: Appendiceal orifice polyps are rare with prevalence of 0.08%. Surgical approach is the standard approach. Endoscopic transcecal appendectomy (ETA) has several potential advantages when compared to surgery and an alternative to non-surgical candidates. In this study, we review the efficacy and safety of ETA for the management of appendiceal lesions.

METHODS: A systematic literature search was conducted across MEDLINE/PubMed, Embase, Scopus, Web of Science, and Cochrane databases. Three studies were included. The primary outcome was the efficacy of ETA in achieving technical success and

RESULTS: A total of three studies were included. A total of 45 patients were included. The mean age was 61.8±14.22 years. Tubular adenoma was the most common pathology, with 12 adenomas. The technical success rate was 100% [95% confidence interval (CI): 92-100%]. The

CONCLUSIONS: This meta-analysis shows that ETA is a promising, minimally invasive technique for appendiceal polyps. It demonstrated high technical success rates in the included series. It also showed promising safety profile with minimal complications reported.

Volume

11

First Page

90

Last Page

90

DOI

10.21037/tgh-2026-0003

ISSN

2415-1289

PubMed ID

42592633

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