Trajectory of Premature Ventricular Complexes With Pregnancy and Cardiomyopathy.

Document Type

Article

Publication Date

7-9-2025

Publication Title

JACC. Case reports

Abstract

BACKGROUND: Premature ventricular complexes (PVCs) are influenced by hormonal fluxes during pregnancy and postpartum. However, the burden and trajectory of PVCs during these periods and subsequent pregnancies are not studied.

CASE SUMMARY: A 35-year-old woman developed frequent PVCs and nonischemic cardiomyopathy during her initial pregnancy. Her PVC burden and cardiac function were closely monitored during postpartum and subsequent pregnancy. Catheter ablation was offered, and she reported a second pregnancy before ablation scheduling. An implantable loop recorder was placed to track her PVC burden closely. This correlated with changes in ejection fraction during pregnancy.

DISCUSSION: We highlighted the changes in PVC burden during pregnancy and postpartum. This emphasizes the need for careful patient education and possible intervention during the interpregnancy intervals. Longitudinal monitoring may offer comprehensive real-time feedback during this period.

TAKE-HOME MESSAGES: Physiological changes in pregnancy and postpartum can exacerbate PVCs, potentially worsening cardiac function. Continuous monitoring may add value.

Volume

30

Issue

18

First Page

103930

DOI

10.1016/j.jaccas.2025.103930

ISSN

2666-0849

PubMed ID

40645729

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