An Unusual Cause of Abdominal Pain: Mesenteric Lymphadenopathy Secondary to Sarcoidosis Without Pulmonary Involvement.

Authors

Brandon Wiggins
Chris Cenzer
John M Sullivan
Kyle Knight
Fady Banno, Corewell Heath East Fellow
Nathan Landesman

Document Type

Article

Publication Date

6-11-2025

Publication Title

Cureus

Abstract

Sarcoidosis is a systemic disease that affects multiple organs in the body but rarely affects the gastrointestinal (GI) tract. The symptoms of GI sarcoidosis may be nonspecific or silent. Often, it is discovered on computed tomography (CT) or esophagogastroduodenoscopy (EGD), and a biopsy is needed for diagnosis. Initial management is typically with prednisone; however, here, we present a rare case of GI sarcoidosis with mesenteric lymphadenopathy in the absence of pulmonary involvement, diagnosed via biopsy and treated successfully with methotrexate.

Volume

17

Issue

6

First Page

e85797

Recommended Citation

Wiggins B, Cenzer C, Sullivan JM, Knight K, Banno F, Landesman N. An unusual cause of abdominal pain: mesenteric lymphadenopathy secondary to sarcoidosis without pulmonary involvement. Cureus. 2025 Jun 11;17(6):e85797. doi: 10.7759/cureus.85797. PMID: 40656382

DOI

10.7759/cureus.85797

ISSN

2168-8184

PubMed ID

40656382