Diagnostic Coronary Angiography Performed with a Novel Miniaturized Robotic System: A Pre-Clinical Feasibility Study

Document Type

Conference Proceeding

Publication Date

10-2025

Publication Title

Journal of the American College of Cardiology

Abstract

BACKGROUND: A novel miniaturized robot (m-robot) has been developed as a disposable, single-use endovascular robot, but its ability to perform diagnostic coronary angiography has not been previously investigated. This pre-clinical study evaluated the technical feasibility of using the m-robot to perform coronary angiography.

METHODS: Procedures were performed on a high-fidelity endovascular simulator (VIST G7, Mentice) that simulates real-time coronary interventions. Eighteen consecutive cases were attempted robotically by the m-robot (LIBERTY® Endovascular Robotic System, Microbot access site to the ascending aorta. All subsequent catheter movements to engage the coronary ostia were performed robotically. Endpoints included procedural success (defined as robotic advancement, retraction, and torquing of catheters to perform coronary angiography without conversion to a manual procedure) and catheter engagement time (time from catheter manipulation in the ascending aorta to coronary engagement confirmed by contrast injection). Engagement times for robotic cases were compared to those of a manual control group.

RESULTS: Among consecutive cases (56% left coronary, 44% right coronary) the feasibility of using the m-robot to robotically manipulate catheters to engage the coronary arteries was demonstrated in all cases. Thus, procedural success was 100%. Robotic coronary angiography was performed with a median engagement time of 24.8 [17.0, 33.1] s, which was significantly slower than the median engagement time of 11.3 [8.4, 13.1] s in manual cases (p = < 0.001).

CONCLUSION: In this pre-clinical investigation, the technical feasibility of robotic coronary using the m-robot was demonstrated with a procedural success of 100%. Although engagement times were significantly longer than those performed manually, median robotic engagement time was less than 30 seconds. These results will be used to design future in vivo studies exploring robotic coronary angiography, including in telerobotic applications.

Volume

86

Issue

17 Suppl

First Page

B195

Comments

American College of Cardiology Thirty-Seventh Annual Transcatheter Cardiovascular Therapeutics Symposium, October 25-28, 2025, San Francisco, CA 

Last Page

B196

DOI

10.1016/j.jacc.2025.09.566

ISSN

1558-3597

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