Acute Leaflet Dysfunction in Transcatheter Pulmonary Valves.

Authors

• Asad Qadir, Corewell Health West
• Lindsey Van Lente, Corewell Health West
• Yasser Al-Khatib, Corewell Health West
• Gruschen R. Veldtman, Corewell Health West

Document Type

Article

Publication Date

9-2026

Publication Title

JACC Case Rep

Abstract

BACKGROUND: Acute leaflet dysfunction after transcatheter pulmonary valve (TPV) implantation is a rare but clinically important complication that remains poorly characterized.

CASE SUMMARY: We report 2 cases of acute stuck leaflet causing significant pulmonary regurgitation immediately postimplantation, the first such cases confirmed with intracardiac echocardiography in the pulmonary position. Case 1 involved a 23-mm Sapien 3 Ultra Resilia valve in a 39-year-old woman with repaired tetralogy of Fallot, requiring emergent valve-in-valve implantation with a 22-mm Melody TPV. Case 2 involved a 25-mm Harmony TPV in a 54-year-old woman, who was managed conservatively and is pending repeat catheterization. Standard rescue maneuvers including balloon dilation and catheter manipulation proved ineffective in both cases.

DISCUSSION: This report highlights the importance of maintaining high clinical suspicion for acute leaflet dysfunction, the utility of intracardiac echocardiography for early diagnosis, and the need for valve-in-valve preparedness during TPV procedures.

Volume

31

Issue

36

First Page

108759

Last Page

108759

Recommended Citation

Qadir A, Van Lente L, Al-Khatib Y, Veldtman GR. Acute leaflet dysfunction in transcatheter pulmonary valves. JACC: Case Reports. 2026;31(36):108759. doi: 10.1016/j.jaccas.2026.108759. PMID: 42720243.

Comments

Helen DeVos Children's Hospital

DOI

10.1016/j.jaccas.2026.108759

ISSN

2666-0849

PubMed ID

42720243