Comparative effectiveness of high-intensity interval training and moderate-intensity continuous training on cardiometabolic health in patients with diabesity: a systematic review and meta-analysis of randomized controlled trials.
Document Type
Article
Publication Date
8-13-2025
Publication Title
Diabetol Metab Syndr
Abstract
OBJECTIVE: To evaluate the effects of high-intensity interval training (HIIT) on cardiometabolic health-related outcomes in patients with type 2 diabetes mellitus and concurrent overweight/obesity (diabesity).
DESIGN: Systematic review and meta-analysis of randomized controlled trials (RCTs).
DATA SOURCES: PubMed, Web of Science, Scopus, Science Direct, Cochrane Library, and Google Scholar databases were searched from inception up to January 31, 2025.
ELIGIBILITY CRITERIA FOR SELECTING STUDIES: RCTs comparing HIIT alone ≥ 2 weeks in duration with moderate-intensity continuous training (MICT). Participants were adults with diabesity.
RESULTS: A total of 26 RCTs qualified, involving 790 patients (50/50 female/male ratio; age: 59.8 ± 12.9 years; body mass index: 28.9 ± 4.2 kg/m
CONCLUSIONS: The present findings suggest that HIIT may serve as an adjunctive non-pharmaceutical management solution for patients with diabesity. Open Science Framework registry: https://osf.io/9by24.
Volume
17
Issue
1
First Page
331
Last Page
331
Recommended Citation
Al-Mhanna SB, Poon ET, Franklin BA, Tarnopolsky MA, Hawley JA, Jakicic JM et al Comparative effectiveness of high-intensity interval training and moderate-intensity continuous training on cardiometabolic health in patients with diabesity: A systematic review and meta-analysis of randomized controlled trials. Diabetol Metab Syndr. 2025 Aug 13;17(1):331. doi: 10.1186/s13098-025-01909-z. PMID: 40804647
DOI
10.1186/s13098-025-01909-z
ISSN
1758-5996
PubMed ID
40804647