Preoperative MELD-XI Score and Risk of Heart Failure After Mitral Valve Surgery for Degenerative Mitral Regurgitation.

Authors

• Yuki Nakamura
• Tomoki Sakata
• Scott H Koeneman
• Keshava Rajagopal
• Vakhtang Tchantchaleishvili
• Konstadinos A Plestis
• John W Entwistle
• Joseph E Bavaria
• Rakesh M. Suri, Corewell Health East

Document Type

Article

Publication Date

11-4-2026

Publication Title

Annals of thoracic surgery short reports

Abstract

BACKGROUND: This study aimed to assess the association between the Model for End-Stage Liver Disease excluding international normalized ratio (MELD-XI) score and heart failure (HF) after isolated mitral valve surgery for degenerative mitral valve regurgitation (dMR).

METHODS: Patients undergoing mitral valve surgery for dMR were divided into groups of high MELD-XI score (>11, n = 28) and low MELD-XI score (≤11, n = 144). The primary end point was early HF events, defined as operative mortality, use of mechanical circulatory support, and prolonged use of inotropic agents after the surgery. The secondary end point was a composite outcome consisting of all-cause mortality and HF admission. The median follow-up period was 338 (70-789) days.

RESULTS: Thirty-day mortality rate was 0.7% in the low MELD-XI score group and 3.6% in the high MELD-XI score group (

CONCLUSIONS: In patients undergoing isolated mitral valve surgery for dMR, elevated preoperative MELD-XI score was associated with an increased risk of early HF events and the composite outcome.

Volume

4

Issue

2

First Page

607

Last Page

612

Recommended Citation

Nakamura Y, Sakata T, Koeneman SH, Rajagopal K, Tchantchaleishvili V, Plestis KA et al [Suri RM] Preoperative MELD-XI Score and Risk of Heart Failure After Mitral Valve Surgery for Degenerative Mitral Regurgitation. Ann Thorac Surg Short Rep. 2025 Nov 4;4(2):607-612. doi: 10.1016/j.atssr.2025.09.035. PMID: 42267041

DOI

10.1016/j.atssr.2025.09.035

ISSN

2772-9931

PubMed ID

42267041